俞志刚 教授,硕士生导师
电话:
电子信箱:yzgyh@126.com
学习经历:
1987-1990年,长春师范大学(化学教育)
2001-2004年,哈尔滨师范大学理学硕士(无机化学)
2005-2009年,哈尔滨工业大学工学博士(化学工程与技术)
2012-2013年,美国University of Nebraska-Lincoln大学访问学者(分析化学)
2015-2016年,美国University of Nebraska-Lincoln大学访问学者(分析化学)
主要社会兼职 :
黑龙江省分析测试学会理事;河北省科学技术奖励省外评审专家
主要研究方向:
1. DNA纳米技术与功能分子器件方面的研究工作,主要包括:光、电化学DNA传感器;DNA测序,适配体-靶标复合物结构鉴定,原子力-拉曼联用成像技术应用研究。
2. 中药材质量评价体系的建立与应用;液相色谱-高分辨质谱联用技术在中药材检测中的应用。
科研获奖:
1. 俞志刚(3/4), 低维纳米材料光电磁性质的结构与性能关系研究,黑龙江省高校科学技术奖三等奖,2018
2. 俞志刚(1/1), 结构模式对目标物诱导信号探针迁移DNA传感器综合性能影响机制的研究,重庆市自然科学优秀学术论文,2018
3. 俞志刚(1/1), 基于保护-取代-杂交模式“信号增益型”电化学传感器检测乙肝B型病毒基因序列的研究,重庆市自然科学优秀学术论文,2017
4. 俞志刚(4/5), 多酸功能材料的制备及其电化学传感器的构建,黑龙江省科学技术奖二等奖,2015
5. 俞志刚(3/4), 多酸功能材料的制备及其电化学传感器的构建,黑龙江省高校科学技术奖二等奖,2015
6. 俞志刚(1/1), 功能化基因点突变检测的电化学DNA生物传感器,哈尔滨市自然科学技术学术成果奖二等奖,2014
7. 俞志刚(1/1), 功能化单碱基错配识别的电化学DNA生物传感器,哈尔滨市自然科学技术学术成果奖二等奖,2013
科研项目:
1. 卡那霉素-编辑适体电化学传感器的增敏化定向构型设计与信号机制(1/7),10万,(No. cstc2018jcyjAX0637),2018.08-2021.07,重庆市自然科学基金资助,主持人,在研。
2. 色谱-质谱联用技术在哈尔滨饮水源动态监测中的应用(1/9),5万,(No. E2007-35),2008.01-2010.12,黑龙江省自然科学基金资助,主持人,已结题。
3. 信号增益型电化学DNA生物传感器(1/8),5万,(No. LC2013C04),2014.01-2017.12,黑龙江省留学归国基金资助,主持人,已结题。
4. 新型吲哚席夫碱抗癌药物配合物的合成及与DNA相互作用(1/8),1.5万,(No. 12511084),2010.01-2012.12,黑龙江省教育厅项目资助,主持人,已结题。
5. 新型稀土光频转换材料的合成、表征及其在农膜中的应用研究(1/9),2.5万,(2005AFQXJ07),2008.01-2010.12,哈尔滨市青年科学基金资助,主持人,已结题。
6. LC-MS技术在农作物产品中农药残留检测中的应用(1/8),1.5万,(No. 11511082),2005.01-2007.12,黑龙江省教育厅基金资助,主持人,已结题。
7. 有机废水发酵产氢强化系统的自絮凝产氢菌蛋白质组学研究(2/8),25万,(No. 51078120),2010.01-2013.12,国家自然科学基金资助,已结题。
8. 囊包多酸的多孔轮烷/准轮烷晶态材料的设计合成与性能研究(4/9),25万,(No. 21101045),2013.01-2015.12,国家自然科学青年基金资助,已结题。
9. 利用蛋白质组学策略解析产氢菌自絮凝机理(2/7),4万,(20092303120004),2011.01-2013.12,教育部博士点新教师基金资助,已结题。
10. 天然沸石生物改性技术研究(2/7),7万,(2011RFXXG003),2011.01-2013.12,哈尔滨市优秀学科带头人基金资助,已结题。
11. 基于蛋白质-代谢物调控网络的梅林青霉降解木质素的机制研究(2/9),63万,(No. 21776054),2018.01-2022.12,国家自然科学面上项目基金资助,在研。
12. 基于多酸的无酶生物传感器的构建与应用研究(3/9),85万,(No. 21371041),2014.01-2017.12,国家自然科学面上项目基金资助,已结题。
发表论文:
1. Xianda Han,Zhigang Yu*, Fengqin Li, et al. “Two kanamycin electrochemical aptamer-based sensors using different signal transduction mechanisms: A comparison of electrochemical behavior and sensing performance” Bioelectrochemistry, 2019, 129: 270-277. (SCI, 影响因子:4.474)
2. Fengqin Li,Zhigang Yu*, Xianda Han, et al. “Electrochemical aptamer-based sensors for food and water analysis: A review” Anal. Chim. Acta, 2019, 1051: 1-23. (SCI, 影响因子:5.256)
3. Fengqin Li, Zhi-gang Yu*, Xianda Han, et al. “A signal-on electrochemical aptasensor for highly sensitive and specific detection of kanamycin based on target-induced signalling probe shifting mechanism” Sensor. Actuat. B-Chem., 2018, 273: 480-487. (SCI, 影响因子: 6.393)
4. Zhi-gang Yu, A.L. Sulief, R.Y. Lai. “Towards the development of a sensitive and selective electrochemical aptamer-based ampicillin sensor”Sensor. Actuat. B-Chem., 2018, 258: 722-729. (SCI, 影响因子: 6.393)
5. Zhi-gang Yu, Rebecca Y. Lai* “A reagentless and reusable electrochemical aptamer-based sensor for rapid detection of ampicillin in complex samples” Talanta, 2018, 176: 619-624. (SCI, 影响因子: 4.916)
6. Xiang Yu, Zhigang Yu*, Fengqin Li, et al. “Effect of structure on sensing performance of a target induced signaling probe shifting DNA-based (TISPS-DNA) sensor” Biosens. Bioelectron., 2017, 91: 817-823. (SCI, 影响因子: 9.518)
7. Yan-mei Xu, Feng-qin Li, Zhi-gang Yu*, et al. “A dual-probe surface-co-immobilization-based electrochemical sensor for highly sensitive and tunable specific detection of a designated DNA” Sensor. Actuat. B-Chem., 2017, 239, 786-794. (SCI, 影响因子: 6.393)
8. Feng-qin Li, Yanmei Xu, Zhi-gang Yu*, et al. “Effect of the duplex length on the sensing performance of a displacement-based electrochemical nucleic acid sensor with an adjustable point mutation discrimination function” Sensor. Actuat. B-Chem., 2016, 234: 648-657. (SCI, 影响因子: 6.393)
9. Wei-ying Zheng, Yan-hui Chen, Xiao-ting Zhang, Zhi-gang Yu* “Analysis of volatiles in paeonia obovata flowers by HS-SPME-GC-MS” Chem. Nat. Compd., 2016, 52: 922-923. (SCI, 影响因子: 0.567)
10. Fengqin Li, Yanmei Xu, Zhigang Yu*, et al. “A “signal on” protection-displacement-hybridization-based electrochemical hepatitis B virus gene sequence sensor with high sensitivity and peculiar adjustable specificity” Biosens. Bioelectron., 2016, 82: 212-216. (SCI, 影响因子: 9.518)
11. Weiying Zheng, Fengqin Li, Zhigang Yu*, et al. “Performance assessment of solvent extraction coupled with gas chromatography-mass spectrometry for the analysis of volatile components from Syringa flowers” Anal. Methods-UK, 2016, 8: 3155-3122. (SCI, 影响因子: 2.378)
12. Fengqin Li, Zhigang Yu*, Yanmei Xu, et al. “Using the synergism strategy for highly sensitive and specific electrochemical sensing of Streptococcus pneumonia Lyt-1 gene sequence” Anal. Chim. Acta, 2015, 886: 175-181. (SCI, 影响因子: 5.256)
13. Feng-qin Li, Zhi-gang Yu*, Xiang Yu, et al. “Using the synergism strategy of multi-redox-modified signaling probe, background suppression and large surface area electrode for highly sensitive and specific electrochemical sensing of specific DNA sequence” Sensor. Actuat. B-Chem., 2015, 220: 1-4. (SCI, 影响因子: 6.393)
14. Fengqin Li, Zhi-gang Yu*, Haichao Qu, et al. “A highly sensitive and specific electrochemical sensing method for robust detection of Escherichia coli lac Z gene sequence” Biosens. Bioelectron., 2015, 68: 78-82. (SCI, 影响因子: 9.518)
15. Zhi-gang Yu*, Anita J. Zaitouna, Rebecca Y. Lai* “Effect of redox label tether length and flexibility on sensor performance of displacement-based electrochemical DNA sensors” Anal. Chim. Acta, 2014, 812: 176-183. (SCI, 影响因子: 5.256)
16. Zhi-gang Yu, Rebecca Y. Lai* “Effect of signaling probe conformation on sensor performance of a displacement-based electrochemical DNA sensor” Anal. Chem., 2013, 85: 3340-3346. (SCI, 影响因子: 6.35)
17. Zhi-gang Yu, Rebecca Y. Lai* “A reagentless and reusable electrochemical DNA sensor based on target hybridization-induced stem-loop probe formation” Chem. Commun., 2012, 48: 10523-10525. (SCI, 影响因子: 6.164)
18. Yu Zhi-gang, Liu Bo, Jiang Zhao-hua*, Zhang Gui-ling “Simultaneous determination of herbicide mefenacet and its metabolites residues in river water by solid phase extraction and rapid resolution liquid chromatography-mass spectrometry with pre-column derivatization” J. Chromatogr. A, 2009, 1216(15): 3090-3097. (SCI, 影响因子: 3.858)
19. Zhi-gang Yu*, Wei-Min Ding, Yan-Hui Chen, et al. “Oxidized multi-walled carbon nanotubes as SPE sorbent for determination of mefenacet and its degradation products residues in water samples by RRLC-UV-ESI-MS” Chromatographia, 2010, 72: 33-38. (SCI, 影响因子: 1.552)
20. Zhi-gang Yu*, Zhi Qin, Hong-rui Ji, et al. “Application of SPE using multi-walled carbon nanotubes as adsorbent and rapid resolution LC-MS--MS for the simultaneous determination of 11 triazine herbicides residues in river water” Chromatographia, 2010, 72: 1073-1081. (SCI, 影响因子: 1.552)
21. Yu Zhi-gang*, Ding Weimin, Ji Hongrui, et al.“Synthesis and antibacterial activity of the Schiff base derived from 1-(p-Chlorophenyl)-3-phenyl-4-benzoyl-pyrazolone-5 and amino compounds and their transitional metallic copper complexes” Chinese J. Org. Chem., 2010, 30(9): 1358-1365. (SCI, 影响因子: 0.567)
22. Yu Zhi-gang, Liu Bo, Jiang Zhao-hua* “Synthesis, characterization by spectra and identification by HPLC-MS of Schiff bases derived from 1-phenyl-3-methyl-4- naphthylaceto-4,5-dihydropyal-5-one (PMNAP) and 2-a-minobenzimidazole (2-AB) and its transitional metallic complexes” Chinese J. Org. Chem., 2009, 29(8): 1217-1222. (SCI, 影响因子: 1.552)