杨桂欣 副教授，硕士生导师；
电话：0451-86392713
电子信箱：yangguixin1988@sina.com
学习经历：
2007-2011年，吉林化工学院学士（英语/化学工程与工艺）
2011-2015年，哈尔滨工程大学（材料科学与工程）
2016-至今，哈尔滨工程大学博士后（光学）
主要研究方向：
1. 无机功能材料的合成方面的研究工作，主要包括：光磁性能的金属氟化物、氧化物或核壳结构稀土上转换纳米复合材料，再对材料的表面进行亲水修饰合成与性质研究。
2. 抗癌方面的研究工作，主要包括：无机功能材料在抗癌诊疗方向的应用。
科研获奖：
1．杨桂欣（3/5）, 稀土上转换发光材料的构筑及抗肿瘤性能研究，黑龙江省科学技术奖一等奖，2017
2. 杨桂欣（5/6）, 空壳结构多功能介孔材料的设计合成及在靶向可控药物缓释领域的应用，哈尔滨市科学技术奖三等奖，2016
科研项目：
1、上转换近红外长余辉发光纳米诊疗体系的构建、成像及靶向抗肿瘤研究
（1/8），26万，(No.51702070)，2018.01-2020.12，国家自然科学基金资助,主持人。
2、基于上转换近红外长余辉发光纳米诊疗体系的构建及抗肿瘤研究（1/8），5万，(No.QC2017006)，2017.10-2020.10，黑龙江省基金资助,主持人。
3、多级核壳结构纳米复合材料的构筑及抗肿瘤性能研究（1/5），10万，(No.2017RAQXJ077)，2017.09-2020.09，哈尔滨市科技局青年后备人才项目,主持人。
4、基于近红外长余辉发光纳米诊疗体系的构建及抗肿瘤研究（1/8），8万，（No.2016M600241），2017.01-2020.01，国家博士后基金资助,主持人。
5、上转换纳米复合材料的构筑及抗肿瘤性能研究（1/7），15万，(No.2501050609)，2017.06-2019.03, 国家博士后基金特别资助，主持人。
6、长余辉发光纳米功能材料用于成像制导的多模式协同抗癌研究（1/7），20万，(No.LBH- TZ1709)，2018.01-2019.12，黑龙江省博士后基金特别资助，主持人。
7、几种纳米功能材料的合成及成像、肿瘤治疗 性能研究（1/8）,5万，（LBH- Z16050）2017.1-2019.12，黑龙江省博士后基金资助，主持人。
授权发明专利：
1、高温热解法制备磁性纳米复合材料的制备方法ZL201410013041.4 201509 第二发明人。
2、核壳光磁双功能纳米复合材料及制备方法ZL201210422166.3 201712第三发明人。
3、金属有机框架结构的多功能纳米材料及制备方法ZL201510689586.1 201711第四发明人。
4、核壳结构Gd-Si-Ce6多功能介孔纳米复合材料的制备方法ZL201510689590.8 201709第四发明人。
5、一种应用于光动力治疗的纳米复合材料及其制备方法 ZL201410826953.3 201707第五发明人。
6、一种应用于光动力治疗的纳米复合材料及其制备方法 ZL201510689583.8 201711第六发明人。
发表论文：
1．Guixin Yang,Dan Yang, Piaoping Yang*, Ruichan Lv, Chunxia Li, Chongnazhong, Fei He, Shili Gai, Jun Lin*; A Single 808 nm Near-Infrared Light-Mediated Multiple Imaging and Photodynamic Therapy Based on Titania Coupled Upconversion Nanoparticles;Chem. Mater., 2015, 27 (23), 7957 – 7968. (IF: 9.407)
2．Guixin Yang, Ruichan Lv, Fei He, Fengyu Qu, Shili Gai, Shaokang Du, Zibo Wei, Piaoping Yang; A core/shell/satellite anticancer platform for 808 NIR light-driven multimodal imaging and combined chemo-/photothermal therapy; Nanoscale, 2015, 7 (32) 13747 – 13758. (IF: 7.76)
3．Dan Yang, Guixin Yang, Xingmei Wang, Ruichan Lv, Shili Gai, Fei He, Gulzar, Arif, Piaoping Yang*; Y2O3:Yb,Er@mSiO2-CuxS double-shelled hollow spheres for enhanced chemo-/photothermal anti-cancer therapy and dual-modal imaging; Nanoscale, 2015, 7 (28) 12180 – 12191. (IF: 7.76)
4．Dan Yang, Guixin Yang, Shili Gai, Fei He, Guanghui An, Yunlu Dai, Ruichan Lv, Piaoping Yang*;Au-25 cluster functionalized metal-organic nanostructures for magnetically targeted photodynamic/photothermal therapy triggered by single wavelength 808 nm near-infrared light; Nanoscale, 2015, 7 (26) 19568 – 19578. (IF: 7.76)
5．Guixin Yang, Shili Gai, Fengyu Qu, Piaoping Yang*;SiO2@YBO3:Eu3+ Hollow Mesoporous Spheres for Drug Delivery Vehicle; ACS Appl. Mater. Interfaces; 2013, 5 (12) 5788 – 5796. (IF: 7.145)
6．Guixin Yang, Ruichan Lv, Shili Gai, Yunlu Dai, Fei He, Piaoping Yang*; Multifunctional SiO2@Gd2O3:Yb/Tm Hollow Capsules: Controllable Synthesis and Drug Release Properties; Inorg. Chem.; 2014, 53 (20) 10917-10927. (IF: 4.82)
7．Guixin Yang, Fei He, Ruichan Lv, Shili Gai, Ziyong Cheng, Yunlu Dai, Piaoping Yang*;A cheap and facile route to synthesize monodisperse magnetic nanocrystals and their application as MRI agents; Dalton Trans.;44 ( 1); 247 – 253; (IF: 4.177)
8．Fei He, Guixin Yang, Piaoping Yang*, Yuxiu Yu, Ruichan Lv, Chunxia Li, Yunlu Dai, Shili Gai, Jun Lin*, A new single 808 nm NIR light-induced imaging-guided multifunctional cancer therapy platform, Adv. Funct. Mater.; 2015, 25, 3966-3976. (IF:11.805)
9． Dan Yang, Guixin Yang, Piaoping Yang*, Ruichan Lv, Shili Gai, Chunxia Li, Fei He, Jun Lin*, Assembly of Au Plasmonic Photothermal Agent and Iron Oxide Nanoparticles on Ultrathin Black Phosphorus for Targeted Photothermal and Photodynamic Cancer Therapy, Adv. Funct. Mater., 2017, Just Accepted. (IF:11.805)
10．Ruichan Lv, Guixin Yang, Fei He,* Yunlu Dai, Shili Gai, Piaoping Yang*. LaF3:Ln mesoporous spheres: controllable synthesis, tunable luminescence and application for dual-modal chemo-/photo-thermal therapy. Nanoscale, 2014, 6, 14799–14809. (IF: 6.739)
11．Dan Yang, Guixin Yang, Shili Gai, Fei He, Ruichan Lv, Yunlu Dai, Piaoping Yang*, Imaging-Guided and Light-Triggered Chemo-/Photodynamic/Photothermal Therapy Based on Gd (III) Chelated Mesoporous Silica Hybrid Spheres, ACS Biomater. Sci.; 2016, 2 (11), 2058 – 2071;
12．Hongbo Fu, Guixin Yang, Shili Gai, Na Niu, Fei He, Jie Xu, Piaoping Yang*. Color-tunable and enhanced luminescence of well-defined sodium scandium fluoride nanocrystals. Dalton Trans., 2013, 42(22), 7863–7870. (IF: 4.177)
13．Shili Gai, Guixin Yang, Xingbo Li, Chunxia Li, Yunlu Dai, Fei He, Piaoping Yang*.Facile synthesis and up-conversion properties of monodisperse rare earth fluoride nanocrystals.Dalton Trans., 2012, 41(38), 11716–11724. (IF: 4.177)
14．Ruichan Lv, Guixin Yang, Shili Gai*, Yunlu Dai, Fei He, Piaoping Yang*.Multifunctional LaPO4:Ce/Tb@Au mesoporous microspheres: synthesis, luminescence and controllable light triggered drug release. RSC Adv., 2014, 4 (108), 63425–63435. (IF: 3.708)
15．Ruichan Lv, Guixin Yang, Fei He, Yunlu Dai, Shili Gai, Piaoping Yang*, Mesoporous NaYF4:Yb,Er@Au-Pt(IV)-FA nanospheres for dual-modal imaging and synergistic photothermal/chemo-anti-cancer therapy. RSC Adv., 2015, 5 (54), 43391 – 43401. (IF: 3.708)
16．Ruichan Lv, Guixin Yang, Yunlu Dai, Shili Gai, Fei He, Piaoping Yang*, Self-produced bubble-template synthesis of La2O3:Yb/Er@Au hollow spheres with markedly enhanced luminescence and release properties. Crystengcomm., 2014, 16 (41), 9612 – 9621. (IF: 3.849)
17．Lili Feng, Fei He, Guixin Yang, Shili Gai, Yunlu Dai, Chunxia Li, Piaoping Yang*. NIR-driven graphitic-phase carbon nitride nanosheets for efficient bioimaging and photodynamic therapy. J. Mater. Chem. B, 2016, 4 (48), 8000 – 8008. (IF: 4.872)
18．Lili Feng, Fei He, Bin Liu, Guixin Yang, Shili Gai, Piaoping Yang*, Chunxia Li, Yunlu Dai, Ruichan Lv, Jun Lin*, g-C3N4 Coated Upconversion Nanoparticles for 808 nm Near-Infrared Light Triggered Phototherapy and Multiple Imaging. Chem. Mater., 2016, 28 (21), 7935 – 7946. (IF: 9.407)
19．Fei He, Lili Feng, Piaoping Yang*, Bin Liu, Shili Gai, Guixin Yang, Yunlu Dai, Jun Lin*. Enhanced up/down-conversion luminescence and heat: Simultaneously achieving in one single core-shell structure for multimodal imaging guided therapy. Biomaterials, 2016, 105, 77 – 78. (IF: 8.387)
20．Ruichan Lv, Dan Yang, Piaoping Yang*, Jiating Xu, Fei He, Shili Gai, Chunxia Li, Yunlu Dai, Guixin Yang, Jun Lin*. Integration of Upconversion Nanoparticles and Ultrathin Black Phosphorus for Efficient Photodynamic Theranostics under 808 nm Near-Infrared Light Irradiation. Chem. Mater., 2016, 28(13), 4724 – 4734. (IF: 9.407)
21．Huiting Bi, Yunlu Dai, Ruichan Lv, Chongna zhong, Fei He, Shili Gai, Arif Gulzar, Guixin Yang, Piaoping Yang*. Doxorubicin-conjugated CuS nanoparticles for efficient synergistic therapy triggered by near-infrared light. Dalton Trans., 2016, 45(12), 5101–5110. (IF: 4.177)
22．Ruichan Lv, Chongna Zhong, Arif Kuhan Gulzar, Fei He, Rui Gu, Shili Gai, Shenghuan Zhang, Guixin Yang, Piaoping Yang*.Near-infrared light-induced imaging and targeted anti-cancer therapy based on a yolk/shell structure. RSC Adv., 2016, 6 (26), 21590 – 21599. (IF: 3.708)
23．Ruichan Lv, Chongna Zhong, Rumin Li, Piaoping Yang*, Fei He, Shili Gai, Zhiyao Hou, Guixin Yang, Jun Lin*. Multifunctional anticancer platform for multimodal imaging and visible light driven photodynamic/photothermal therapy. Chem. Mater.,2015, 27 (5), 1751–1763. (IF: 9.407)
24．Ruichan Lv，Piaoping Yang，Fei He，Shili Gai，Chunxia Li，Yunlu Dai，Guixin Yang，Jun Lin ，A Yolk-like Multifunctional Platform for Multimodal Imaging and Synergistic Therapy Triggered by a Single Near-Infrared Light，ACS Nano., 2015, 9 (2)：1630-1647. (IF:13.334)
25．Ruichan Lv, Piaoping Yang*, Fei He, Shili Gai, Guixin Yang, Jun Lin*. Hollow structured Y2O3:Yb/Er-CuxS nanospheres with controllable size for simultaneous chemo/photothermal therapy and bio-imaging.Chem. Mater., 2015, 27 (2), 483–496. (IF: 9.407)
26．Ruichan Lv, Chongna Zhong, Arif Gulzar, Shili Gai, Fei He, Rui Gu, Shenghuan Zhang, Guixin Yang Piaoping Yang*. Synthesis, luminescence, and anti-tumor properties of MgSiO3:Eu-DOX-DPP-RGD hollow microspheres. Dalton Trans., 2015, 44 (42), 18585–18595. (IF: 4.177)
27．Na Niu, Fei He, Pingan Ma, Shili Gai, Guixin Yang, Fengyu Qu, Yan Wang, Jie Xu, Piaoping Yang* , Up-conversion nanoparticles assembled mesoporous silica composites: synthesis plasmon-enhanced luminescence;and near-infrared light triggered drug release, ACS Appl. Mater. Interfaces, 2014, 6 (5), 3250-3262. (IF:7.145)
28．Jie Xu, Shili Gai*, Ping'an Ma, Yunlu Dai, Guixin Yang, Fei He, Piaoping Yang*. Gadolinium fluoride mesoporous microspheres: controllable synthesis, materials and biological properties. J. Mater. Chem. B, 2014, 2(13), 1791–1801.(IF: 4.872)
29．Fei He, Na Niu, Lin Wang, Jie Xu, Yan Wang, Guixin Yang, Shili Gai, Piaoping Yang. Influence of surfactants on the morphology; upconversion emission; and magnetic properties of beta-NaGdF4:Yb3+;Ln3+ (Ln = Er; Tm; Ho). Dalton Trans., 2013, 42(27), 10019-10028. (IF:4.177)
30．Ruichan Lv, Piaoping Yang*, Fei He, Shili Gai, Guixin Yang, Yunlu Dai, Zhiyao Hou, Jun Lin*. An imaging-guided platform for synergistic photodynamica/photothermal/chemotherapy with pH/temperature-responsive drug release. Biomaterials. 63, 115 – 127.(IF:8.387)
31．Piaoping Yang,Dan Yang, Guixin Yang, Shili Gai, Fei He, Chunxia Li. Multifunctional Theranostics for Dual-Modal Photodynamic Synergistic Therapy via the Stepwise Water Splitting. ACS Appl. Mater. Interfaces. (IF:7.145)